| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human C Reactive Protein was used as the immunogen for the CRP antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
CRP Antibody / C Reactive Protein is a anti-CRP Rabbit antibody Recombinant Rabbit Monoclonal clone 32C44 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human.
Key elements and design rationale
- Target: CRP
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 32C44, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB
Biological background
CRP antibody is widely applied in immunology, cardiology, and translational medicine. In clinical diagnostics, CRP is measured to monitor infection, sepsis, and chronic inflammatory diseases. High sensitivity CRP assays provide prognostic information in cardiovascular disease, linking elevated CRP levels to increased risk of myocardial infarction and stroke. By detecting CRP, researchers and clinicians can evaluate systemic inflammatory responses and disease severity.
ELISA with CRP antibody allows quantitative measurement of serum concentrations. Immunohistochemistry detects CRP deposition in tissues, while western blotting confirms protein expression and isoform detection. These methods support research into CRP biology and clinical monitoring of inflammatory states.
Beyond its diagnostic utility, CRP plays roles in innate immunity by bridging recognition of pathogens with activation of complement and Fc receptor mediated pathways. It contributes to clearance of apoptotic cells and immune complexes. Dysregulation of CRP expression or function is implicated in autoimmunity and chronic inflammatory disease. By applying CRP antibody, scientists can investigate how this acute phase protein contributes to host defense and pathology.
CRP antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
