| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| Target |
Compound Overview
CXJ-2 (CAS 2919976-92-2) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2919976-92-2 |
|---|---|
| Molecular Formula | C55H87N15O22 |
| Molecular Weight | 1310.37 g/mol |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
CXJ-2, a cyclic peptide, demonstrates moderate affinity for elastin-derived peptides (EDPs) and exhibits potent inhibition of the PI3K/ERK pathway, alongside significant reduction in hepatic stellate cell proliferation and migration, conferring strong antifibrotic efficacy (1).
Target(s): PI3K
Signaling pathway(s): PI3K/Akt/mTOR signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
Half-maximal inhibitory concentration (IC50) refers to the concentration of the inhibitor which is required to inhibit a given biological or biochemical function by half.
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