| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | DL-amino-5-phosphonopentaoic acid sodium salt |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in water |
| Source | Synthetic |
| Storage |
D-LAP5.Na is the sodium salt form of D-2-Amino-5-phosphonopentanoic acid, a selective NMDA receptor antagonist. It inhibits glutamate-induced excitotoxicity by blocking NMDA receptor activation, a process implicated in the pathogenesis of neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. The sodium salt enhances solubility and bioavailability, making it suitable for in vivo studies. D-LAP5.Na is used to study synaptic plasticity, neuroprotection, and the molecular basis of cognitive decline.
Classification: Not WHMIS controlled.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
D-LAP5.Na (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-414)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Schulte M., Roon R., Chalmers D., Sunter D., & Koerner J. (1994) Brain Res. 203-7.
