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Compound Overview
Deruxtecan analog 2 (CAS 1599440-10-4) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 1599440-10-4 |
|---|---|
| Molecular Formula | C29H30FN5O7 |
| Molecular Weight | 579.58 g/mol |
| SMILES | N(C(COCNC(CN)=O)=O)(CH)1C2=C3C(C=4N(C3)C(=O)C5=C(C4)(C)(CC)(O)C(=O)OC5… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Deruxtecan Analog 2 (example 9 P3), a Deruxtecan derivative, serves as an agent-linker conjugate integrating Camptothecin (CPT), a Topo I inhibitor active against colorectal, breast, lung, and ovarian cancers, with a distinct linker. This analog is employed in synthesizing anti-FGFR2 ADC (1).
Target(s): Others, Drug-Linker Conjugates for ADC
Signaling pathway(s): Others, Antibody-drug Conjugate/ADC Related
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
After the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.
Stock concentration (mM) = [mass (mg) × 1000] / [MW (g/mol) × volume (mL)]. Example: to prepare 10 mM stock from 5 mg of a 500 g/mol compound: volume = (5 × 1000) / (500 × 10) = 1 mL DMSO. For working solutions, dilute the DMSO stock into assay buffer: C₁V₁ = C₂V₂. For a 1 µM working solution from a 10 mM stock in a 1 mL assay volume, add 0.1 µL of stock (or pre-dilute to an intermediate concentration first).
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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