| Field | Specification |
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| Product Type | |
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Compound Overview
DIBAC-GGFG-NH2CH2-Dxd (CAS 2758875-01-1) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2758875-01-1 |
|---|---|
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a derivative of Camptothecin, serves as a linker-payload for protein-agent conjugates (1). It is utilized as a payload in the antibody-coupling drug ADC (DS-8201a). Additionally, this compound functions as a click chemistry reagent due to its DBCO group, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-group-containing molecules.
Target(s): Others, Drug-Linker Conjugates for ADC
Signaling pathway(s): Antibody-drug Conjugate/ADC Related, Others
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Use a bath-type ultrasonic cleaner at standard cleaning frequency (37–40 kHz). Bath sonication is gentler than a probe sonicator and avoids sample overheating. Sonicate in 5–10 second intervals, checking solubility between pulses, for no more than 2–3 minutes total. Warm the bath to 37 °C if solubility remains poor.
Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
