| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | C2 Dihydroceramide, D-erythro-N-Acetylsphinganine |
| Cas No. | |
| Form | White solid. |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in ethanol (5 mg/ml) or DMSO (5 mg/ml: dissolve in hot DMSO, then cool to RT). |
| Source | Synthetic |
| Storage |
Dihydroceramide is a precursor in the ceramide biosynthesis pathway and plays a key role in sphingolipid metabolism. In neuroscience, dihydroceramide has gained attention for its involvement in cellular stress responses, apoptosis, and autophagy—processes that are dysregulated in neurodegenerative diseases. Altered levels of dihydroceramide have been linked to mitochondrial dysfunction and oxidative stress in neuronal cells. Its role in modulating membrane dynamics and signaling pathways makes it a valuable molecule for studying lipid-mediated mechanisms in neurodegeneration and brain aging.
Classification: Not WHMIS controlled.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Dihydroceramide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-398)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Jiang, Q. et al. (2012). Int J Cancer, 130(3): 685-93.
3. Signorelli, P. et al. (2009). Cancer Lett, 282(2): 238-43.
