| Field | Specification |
|---|---|
| Target | |
| Alternative names | Dipeptidyl peptidase 4|ADABP|Adenosine deaminase complexing protein 2 (ADCP-2)|Dipeptidyl peptidase IV (DPP IV)|T-cell activation antigen CD26|TP103|Dipeptidyl peptidase 4 membrane form Alternative names: Dipeptidyl peptidase IV membrane form|Dipeptidyl peptidase 4 soluble form Alternative names: Dipeptidyl peptidase IV soluble form|DPP4|ADCP2|CD26 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | dipeptidyl-peptidase 4 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes DPP4. It is validated for ELISA, Western Blot, Immunohistochemistry, Immunofluorescence.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry, Immunofluorescence |
|---|---|
| WB | 1:500-1:1000 |
| IHC | 1:20-1:200 |
| IF | 1:10-1:100 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
dipeptidyl-peptidase 4
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | dipeptidyl-peptidase 4 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 110 kDa |
| UniProt # | P27487 |
| Gene ID | 1803 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Dipeptidyl peptidase 4|ADABP|Adenosine deaminase complexing protein 2 (ADCP-2)|Dipeptidyl peptidase IV (DPP IV)|T-cell activation antigen CD26|TP103|Dipeptidyl peptidase 4 membrane form Alternative names: Dipeptidyl peptidase IV membrane form|Dipeptidyl peptidase 4 soluble form Alternative names: Di |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for DPP4 research from Fine Test, or contact us for alternative formats.
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