| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | F-ara-ATP |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Fludarabine triphosphate (CAS 74832-57-8) is a research-grade small molecule supplied by TargetMol.
Alternative names: F-ara-ATP
Physical Properties
| CAS Number | 74832-57-8 |
|---|---|
| Molecular Formula | C10H15FN5O13P3 |
| Molecular Weight | 525.17 g/mol |
| SMILES | Nc1nc(F)nc2n(cnc12)(CH)1O(CH)(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(CH)(O)(CH… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate , inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Sonication time depends on compound solubility and concentration. In most cases, 1–3 minutes of intermittent bath sonication is sufficient to dissolve small molecule compounds in DMSO. For poorly soluble compounds, warming the solvent to 37–50 °C combined with brief vortexing between sonication pulses can improve dissolution. If the compound remains undissolved, prepare a more dilute stock solution.
mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.
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