GJ103 sodium salt

SKU:BHB20429080
Overview
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GJ103 sodium salt (CAS 1459687-96-7) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 1459687-96-7
Molecular Weight 364.36 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T4251-1MLX10MM 1 mL x 10 mM (in DMSO)
T4251-5MG 5 mg
T4251-10MG 10 mg
T4251-25MG 25 mg
T4251-50MG 50 mg
T4251-100MG 100 mg
T4251-200MG 200 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mL x 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T4251
Activity
  • Kinase Inhibitor
Cas No. 1459687-96-7
Molecular Weight 364.36
Product Type
  • Small Molecule Inhibitor
Signaling Pathway DNA Damage/DNA Repair///PI3K/Akt/mTOR signaling
SMILES (Na+).COc1cccc(c1)-n1c(SCC((O-))=O)nnc1-c1ccccn1
Target ATM/ATR

Compound Overview

GJ103 sodium salt (CAS 1459687-96-7) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 1459687-96-7
Molecular Formula C16H13N4NaO3S
Molecular Weight 364.36 g/mol
SMILES (Na+).COc1cccc(c1)-n1c(SCC((O-))=O)nnc1-c1ccccn1
Form Solid
Shipping Room Temperature (RT)

Biological Activity

GJ103 sodium salt is an active analog of GJ072, a read-through compound. It has been shown to reduce the surface tension of aqueous solutions, which makes it easier for molecules to move through the solution. It has also been shown to reduce the viscosity of aqueous solutions, which makes it easier for molecules to move through the solution. Additionally, it has been shown to reduce the pH of aqueous solutions, which can have a variety of effects on the biochemical and physiological processes of living organisms.

Target(s): ATM/ATR

Signaling pathway(s): DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

How long does sonication usually take?

Sonication time depends on compound solubility and concentration. In most cases, 1–3 minutes of intermittent bath sonication is sufficient to dissolve small molecule compounds in DMSO. For poorly soluble compounds, warming the solvent to 37–50 °C combined with brief vortexing between sonication pulses can improve dissolution. If the compound remains undissolved, prepare a more dilute stock solution.

Can inhibitors be used for cell experiments?

Yes — TargetMol inhibitors can be used in cell-based and in vitro experiments. Prepare a DMSO stock, then dilute into cell culture medium to the desired working concentration, keeping DMSO ≤ 0.1% (v/v) to avoid solvent toxicity. Note that not all compounds have published data for every cell line or assay system; in such cases, perform a dose-response experiment with appropriate positive and vehicle controls to validate efficacy in your specific model.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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