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Compound Overview
Glucocorticoid receptor agonist-1 phosphate Gly-Glu TFA (CAS 2734877-83-7) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2734877-83-7 |
|---|---|
| Molecular Formula | C44H51F3N3O15P |
| Molecular Weight | 949.86 g/mol |
| SMILES | C(C(O)=O)(F)(F)F.C(COP(=O)(O)O)(=O)(C)12(C)3(C)(C)(C(C)1(O(CH)(O2)C4=C… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Glucocorticoid Receptor Agonist-1 Phosphate Gly-Glu (TFA) serves as a cleavable linker for the synthesis of Antibody-Drug Conjugates (ADCs).
Target(s): Others, ADC Linker
Signaling pathway(s): Antibody-drug Conjugate/ADC Related, Others
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Use a bath-type ultrasonic cleaner at standard cleaning frequency (37–40 kHz). Bath sonication is gentler than a probe sonicator and avoids sample overheating. Sonicate in 5–10 second intervals, checking solubility between pulses, for no more than 2–3 minutes total. Warm the bath to 37 °C if solubility remains poor.
Determining the amount based on solution clarity.1. If the prepared solution is clear, it can be prepared in a larger amount for one-time use and stored at 4°C. It is recommended to prepare the solution once a week, as prolonged storage may lead to loss of efficacy. 2. If the prepared solution is a suspension, it is recommended to prepare and use immediately each time.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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