| Field | Specification |
|---|---|
| Target | |
| Alternative names | Guanine nucleotide-binding protein G(i) subunit alpha-2|Adenylate cyclase-inhibiting G alpha protein|GNAI2|GNAI2B |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 2 |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
Guanine nucleotide-binding proteins(G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.
Product Overview
This polyclonal antibody, raised in Rabbit, recognizes GNAI2. It is validated for ELISA, Western Blot, Immunofluorescence, Immunohistochemistry, Immunoprecipitation.
Validated Applications
| Applications | ELISA, Western Blot, Immunofluorescence, Immunohistochemistry, Immunoprecipitation |
|---|---|
| WB | 1:500-1:2000 |
| IP | 1:500-1:2000 |
| IHC | 1:50-1:500 |
| IF | 1:10-1:100 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 2
Specifications
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 2 |
| Purification | Immunogen Affinity Purified |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 35-40 kDa |
| UniProt # | P04899 |
| Gene ID | 2771 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | Guanine nucleotide-binding protein G(i) subunit alpha-2|Adenylate cyclase-inhibiting G alpha protein|GNAI2|GNAI2B |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
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Explore related antibodies and reagents for GNAI2 research from Fine Test, or contact us for alternative formats.
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