| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Golexanolona |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Golexanolone (CAS 2089238-18-4) is a research-grade small molecule supplied by TargetMol.
Alternative names: Golexanolona
Physical Properties
| CAS Number | 2089238-18-4 |
|---|---|
| Molecular Formula | C21H31NO2 |
| Molecular Weight | 329.48 g/mol |
| SMILES | C(C)12(C)3((C)((C)4((C)(C)(CC3)C(=NO)CC4)(H))(CC(C)1(C(C)(CC)(O)CC2)(H… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Golexanolone (Golexanolona) is a novel GABA-A receptor-modulating steroid antagonist that reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in rats with chronic hyperammonemia, and may be used to study hepatic encephalopathy.
Target(s): GABA Receptor
Signaling pathway(s): Neuroscience, Membrane transporter/Ion channel
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Solubility data for each compound is provided on the TargetMol product page and DataSheet, listed as maximum solubility in DMSO and/or aqueous media (mg/mL and mM). For compounds not yet characterized, prepare a test dissolution at the intended stock concentration and visually confirm clarity before use. When preparing aqueous working solutions, always dilute from a DMSO stock and monitor for precipitation at your final assay concentration.
After the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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