| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Gossypolone (CAS 4547-72-2) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 4547-72-2 |
|---|---|
| Molecular Formula | C30H26O10 |
| Molecular Weight | 546.52 g/mol |
| SMILES | C(=O)C1=C2C(=C(C(C)C)C(O)=C1O)C(=O)C(C)=C(C2=O)C=3C(=O)C=4C(C(=O)C3C)=… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
Target(s): Wnt/beta-catenin, Gamma-secretase
Signaling pathway(s): Neuroscience, Proteases/Proteasome, Stem Cells, Cytoskeletal Signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Use a bath-type ultrasonic cleaner rather than a high-intensity ultrasonic disruptor. Bath sonicators provide gentle, uniform agitation appropriate for dissolving solid compounds without generating cavitation damage or excessive heat. Ensure the solvent tube is fully submerged and use short sonication pulses of 5–10 seconds.
Try the following steps: (1) warm the DMSO solvent to 37–50 °C before adding the compound; (2) vortex vigorously for 30 seconds then bath-sonicate for 1–2 minutes; (3) if still undissolved, prepare a more dilute stock. Note that maximum solubility values are reference conditions — actual solubility can vary with temperature, solvent lot, and compound batch. Contact BioHippo support if dissolution problems persist.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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