| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human GRB2 was used as the immunogen for the GRB2 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
GRB2 Antibody / Growth factor receptor-bound protein 2 is an antibody targeting GRB2. Host: Rabbit. Monoclonal. Clone: 32G61. Format: Liquid. Applications: WB, IHC, ICC, IF.
Key elements and design rationale
- Target: GRB2.
- Immunogen: A synthesized peptide derived from human GRB2 was used as the immunogen for the GRB2 antibody..
- Species reactivity: Human, Mouse, Rat.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
GRB2 antibody detects growth factor receptor-bound protein 2, an adaptor protein central to receptor tyrosine kinase (RTK) signaling. GRB2 consists of one SH2 domain flanked by two SH3 domains, enabling it to couple activated receptors to downstream Ras-MAPK pathways.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IHC: tissue distribution assessment; interpret with matched controls.
- IF/ICC: subcellular localization imaging with proper background controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
