| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO |
| Source | Synthetic |
| Storage |
HC-030031 is a selective TRPA1 channel blocker that inhibits calcium influx triggered by irritants such as AITC and formalin. It does not affect other TRP channels or ion channels like TRPV1, TRPV3, TRPV4, hERG, or Nav1.2. In neuroscience, HC-030031 is used to investigate TRPA1's role in pain perception, neuroinflammation, and its potential involvement in neurodegenerative conditions characterized by oxidative stress.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hazard Phrases:
H301
Precautionary Phrases:
P301 + P310
HC-030031 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-303)
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2. Taylor-Clark T.E., et al. (2008) Mol Pharmacol. 73(2): 274-281.
