| Field | Specification |
|---|---|
| Target | |
| Alternative names | 60 kDa heat shock protein, mitochondrial|60 kDa chaperonin|Chaperonin 60 (CPN60)|Heat shock protein 60 (HSP-60, Hsp60)|HuCHA60|Mitochondrial matrix protein P1|P60 lymphocyte protein|HSPD1|HSP60 |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | heat shock 60kDa protein 1(chaperonin) |
| Conjugate | |
| Molecular weight | |
| Purity | |
| Purification | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Scientific Background
HSPD1, also known as HSP60, belongs to the chaperonin family and acts as a chaperone to enhance cell survival under physiological stresses. Hsp60 has been shown to be connected with many aspects of cell functions such as protein folding and assembling of polypeptide chains in mitochondria. Recently it has been reported that HSP60 is associated with apoptosis or inhibition of cancer cell growth.(21822415)
Product Overview
This monoclonal antibody (clone 2C7), raised in Mouse, recognizes HSPD1. It is validated for ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry.
Validated Applications
| Applications | ELISA, Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
|---|---|
| WB | 1:5000-1:50000 |
| IP | 1:1000-1:4000 |
| IHC | 1:50-1:2000 |
| IF | 1:20-1:200 |
Optimal dilutions should be determined by the end user for each application and sample type.
Immunogen
heat shock 60kDa protein 1(chaperonin)
Specifications
| Host | Mouse |
|---|---|
| Clonality | Monoclonal |
| Clone | 2C7 |
| Isotype | IgG1 |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Immunogen | heat shock 60kDa protein 1(chaperonin) |
| Purification | Protein A+G Purification |
| Purity | ≥95% as determined by SDS-PAGE |
| Form | Liquid |
| Target MW | 60 kDa |
| UniProt # | P10809 |
| Gene ID | 3329 |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| Alternative Names | 60 kDa heat shock protein, mitochondrial|60 kDa chaperonin|Chaperonin 60 (CPN60)|Heat shock protein 60 (HSP-60, Hsp60)|HuCHA60|Mitochondrial matrix protein P1|P60 lymphocyte protein|HSPD1|HSP60 |
Reactivity Notes
Validated reactivity: Human, Mouse, Rat. For other species, epitope conservation may allow cross-reactivity; confirm with appropriate controls.
Safety & Handling
This product is for research use only (RUO) and is not intended for diagnostic or therapeutic use. The formulation contains sodium azide; handle with standard laboratory precautions.
Related Products
Explore related antibodies and reagents for HSPD1 research from Fine Test, or contact us for alternative formats.
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