| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Hu7691 (CAS 2360523-76-6) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2360523-76-6 |
|---|---|
| Molecular Formula | C22H22ClF3N4O |
| Molecular Weight | 450.88 g/mol |
| SMILES | N(C(=O)C1=C(F)C=C(C=C1)C2=CC=NN2C)(CH)3(CH)(CCNC3)C4=CC(F)=C(F)C=C4.Cl |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Hu7691 is an orally active, selective and potent Akt inhibitor that inhibits Akt1, Akt2 and Akt3, inhibits proliferation of neuroblastoma cells and induces differentiation of neuroblastoma cells.
Target(s): Akt
Signaling pathway(s): Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.
For currently available products, batch-specific purity data (HPLC chromatogram, NMR spectrum, and Certificate of Analysis) is accessible via the DataSheet link on the product page. For future or custom synthesis products, purity determination is conducted upon availability and published on the product page. Contact BioHippo for batch-specific CoA requests or custom synthesis enquiries.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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