| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Complement C4c, Complement Component C4c, C4c. |
| Form | Sterile Filtered clear solution. |
| Formulation | |
| Product Type | |
| Protein Size | |
| Purity | |
| Source | Human Plasma. |
| Species | |
| Storage | |
| Target |
Human Complement Component C4c is supplied as a recombinant protein for in vitro research use.
Background
Complement C4c is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c. Complement C4c interacts with C1 and C2 to form C3 convertase of the classic activation pathway. Systemic lupus erythematosus (SLE) is often associated with congenital C4 deficiency. Reduced levels of components of the classic pathway (C1, C2, C4, C3) are common after such activation, e.g. in SLE, acute serum sickness and conditions associated with circulating immune complexes.
Product format
Provided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.
Activity & assay information
- Human Virus Test: Plasma from each donor has been tested and found negative for HIV-1 & 2 antibodies, Hepatatis B surface antigen, and Hepatatis C antibodies.
What is the purity of Human Complement Component C4c (Human)?
What buffer / formulation is this protein supplied in?
How should Human Complement Component C4c (Human) be stored?
Is this protein approved for clinical or in vitro diagnostic use?
Can I request a custom size, tag variant, or formulation?
Can’t Find What You’re Looking For? We can help you source the best match or customize a recombinant protein solution for your study. Options may include species (human/mouse/rat), protein region/domain (full-length vs fragment), tag or label (His/GST/FLAG/biotin/fluorescent), expression system (E. coli/HEK293/insect), purity grade, formulation (buffer, carrier-free, glycerol-free), activity/functional validation (binding or enzymatic assays), endotoxin level (low-endotoxin for cell-based work), mutants/variants (point mutations, isoforms), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
