| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Indirubin-3'-monoxime, 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one, Indirubin-3′-oxime |
| Cas No. | |
| Form | Red solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Source | Synthetic |
| Storage |
Indirubin-3'-monoxime is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3β (GSK-3β), both of which are implicated in neurodegenerative diseases. By modulating GSK-3β activity, it may influence tau phosphorylation and neuronal survival, making it a candidate for Alzheimer’s and Parkinson’s disease research. Its ability to regulate cell cycle and kinase signaling pathways also supports its use in studies of neuroprotection and neural regeneration.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Indirubin-3'-monoxime (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-502)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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