KG-501

SKU:BHB20439935
Overview
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KG-501 (CAS 18228-17-6) is a epigenetic modulator supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Epigenetic Modulator
CAS No. 18228-17-6
Molecular Weight 377.72 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T7297-2MG 2 mg
T7297-5MG 5 mg
T7297-1MLX10MM 1 mL x 10 mM (in DMSO)
T7297-10MG 10 mg
T7297-50MG 50 mg
T7297-100MG 100 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 2 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 50 mg, 100 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T7297
Activity
  • Epigenetic Modulator
Alternative Names Naphthol AS-E phosphate
Cas No. 18228-17-6
Molecular Weight 377.72
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Chromatin/Epigenetic
SMILES C(NC1=CC=C(Cl)C=C1)(=O)C=2C(OP(=O)(O)O)=CC3=C(C2)C=CC=C3
Target Epigenetic Reader Domain

Compound Overview

KG-501 (CAS 18228-17-6) is a research-grade small molecule supplied by TargetMol.

Alternative names: Naphthol AS-E phosphate

Physical Properties

CAS Number 18228-17-6
Molecular Formula C17H13ClNO5P
Molecular Weight 377.72 g/mol
SMILES C(NC1=CC=C(Cl)C=C1)(=O)C=2C(OP(=O)(O)O)=CC3=C(C2)C=CC=C3
Form Solid
Shipping Room Temperature (RT)

Biological Activity

KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 uM).

Target(s): Epigenetic Reader Domain

Signaling pathway(s): Chromatin/Epigenetic

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does prolonged sonication affect the compound structure?

It is recommended to sonicate at a lower frequency

How to store the inhibitor solutions?

After the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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