| Field | Specification |
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Compound Overview
M24 (CAS 2761947-05-9) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2761947-05-9 |
|---|---|
| Molecular Formula | C44H40Cl3N5O11S |
| Molecular Weight | 953.24 g/mol |
| SMILES | Cc1cc(OCCOc2ccc(CN3CC(=O)N(CC(=O)N(CH)(Cc4ccc(OCc5ccc(Cl)cc5)cc4)C(=O)… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
M24, a Mcl-1 selective inhibitor, demonstrates strong binding affinity for Mcl-1, evidenced by a K i value of 0.33 uM. It also shows significant anti-proliferative activity and induces apoptosis in HepG2 cells (1).
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Use a bath-type ultrasonic cleaner at standard cleaning frequency (37–40 kHz). Bath sonication is gentler than a probe sonicator and avoids sample overheating. Sonicate in 5–10 second intervals, checking solubility between pulses, for no more than 2–3 minutes total. Warm the bath to 37 °C if solubility remains poor.
Sonication time depends on compound solubility and concentration. In most cases, 1–3 minutes of intermittent bath sonication is sufficient to dissolve small molecule compounds in DMSO. For poorly soluble compounds, warming the solvent to 37–50 °C combined with brief vortexing between sonication pulses can improve dissolution. If the compound remains undissolved, prepare a more dilute stock solution.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
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