MAPKII Kinase Inhibitor

MAPKII Kinase Inhibitor targets MAPKAP kinase II (MK2), a key component of the p38 MAPK pathway involved in cellular stress responses. MK2 is activated by various chemical and biological stressors, including oxidative stress, cytokines, and irradiation. In neurodegenerative disease research, MK2 has emerged as a therapeutic target due to its role in neuroinflammation—a hallmark of conditions such as Alzheimer's and Parkinson's disease. By inhibiting MK2, this compound may attenuate inflammatory signaling cascades and reduce neuronal damage. Its modulation of stress-activated pathways positions it as a promising candidate for intervention in neuroinflammatory and neurodegenerative disorders.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

• S22 - Do not breathe dust
• S24/25 - Avoid contact with skin and eyes
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

MAPKII Kinase Inhibitor (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-120)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

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