Mifepristone (RU486)

SKU:BHB11900040
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Mifepristone (RU486) is a research-grade small-molecule inhibitor of Glucocorticoid for Cancer and Apoptosis studies. Supplied as a yellow solid with >98% purity (CAS 84371-65-3, MW 429.6) Soluble to 100 mM in DMSO, and to 50 mM in ethanol; store at -20°C. For research use only.
Cas No. 84371-65-3
Molecular Formula C29H35NO2
Purity >98%
Application Notes Glucocorticoid antagonist
Options selector
Catalog no. Size
SIH-211-100MG 100 mg
SIH-211-500MG 500 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 100 mg, 500 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-211
Activity
  • Inhibitor
Alternative Names (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)estra-4,9-dien-3-one, RU486, RU 38486
Cas No. 84371-65-3
Form Yellow solid
Molecular Weight 429.6
Product Type
  • Biochemicals
  • Small Molecules
Purity >98%
Shipping Shipped Ambient
SMILES CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O
Solubility Soluble to 100 mM in DMSO, and to 50 mM in ethanol
Source Synthetic
Storage -20ºC

Mifepristone is a progesterone receptor antagonist with antiglucocorticoid and antiandrogen properties. In neuroscience, it is investigated for its role in modulating stress responses and glucocorticoid signaling. Its high affinity for glucocorticoid receptors positions it as a potential modulator of neuroendocrine and neuroinflammatory pathways.

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases:

  • R60- May impair fertility
  • R61- May cause harm to the unborn child

Hazard Phrases:

H360

Precautionary Phrases:

P201-P308 + P313

Mifepristone (RU486) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-211)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Heikinheim O., Kekkonen R. and Lahteenmaki P. (2003) Contraception. 68(6): 421-426.

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