MIPS-21335

SKU:BHB20444785
Overview
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MIPS-21335 (CAS 2569296-51-9) is a small molecule inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Small Molecule Inhibitor
CAS No. 2569296-51-9
Molecular Weight 487.47 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T81791-5MG 5 mg
T81791-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T81791
Activity
  • Small Molecule Inhibitor
Cas No. 2569296-51-9
Molecular Weight 487.47
Product Type
  • Small Molecule Inhibitor
Signaling Pathway PI3K/Akt/mTOR signaling
SMILES O=C(NC1=NC=2C(OC)=C(OCC=3C=CC=C(C3)N(=O)=O)C=CC2C4=NCCN14)C5=CN=C(N)C=C5
Target PI4K

Compound Overview

MIPS-21335 (CAS 2569296-51-9) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 2569296-51-9
Molecular Formula C24H21N7O5
Molecular Weight 487.47 g/mol
SMILES O=C(NC1=NC=2C(OC)=C(OCC=3C=CC=C(C3)N(=O)=O)C=CC2C4=NCCN14)C5=CN=C(N)C=…
Form Solid
Shipping Room Temperature (RT)

Biological Activity

MIPS-21335 is a potent PI3KC2alpha inhibitor with an IC50 value of 7 nM and additionally exhibits inhibitory activity against PI3KC2beta, p110alpha, p110beta, and p110delta with IC50 values of 0.043, 0.140, 0.386, and 0.742 uM, respectively. This compound demonstrates an antithrombotic effect (1).

Target(s): PI4K

Signaling pathway(s): PI3K/Akt/mTOR signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Can high-temperature sterilization be used for inhibitors?

Most small molecule inhibitors are not compatible with autoclaving (121 °C), which can cause thermal decomposition or loss of biological activity. For sterile cell-based experiments, filter-sterilize working solutions through a 0.2 µm membrane after dilution into aqueous buffer. Verify thermal stability in the DataSheet before applying any heat treatment.

Why can't I see anything in the vial when I receive small-sized products?

Due to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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