| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | Recombinant full-length human MPZ protein was used as the immunogen for the MPZ antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
MPZ Antibody / Myelin Protein Zero is an antibody targeting MPZ. Host: Mouse. Monoclonal. Clone: MPZ/7390. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: MPZ.
- Immunogen: Recombinant full-length human MPZ protein was used as the immunogen for the MPZ antibody..
- Species reactivity: Human.
- Localization: Membrane.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
Zero, also known as myelin protein zero (MPZ) is a Type 1 integral membrane glycoprotein that mediates adhesion of spiraling wraps of the myelin sheath in order to ensure stable synaptic transmission. Zero protein encompasses approximately 50% of total protein in the sheath scaffolding in contribution to structural integrity of peripheral myelin.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.