| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
MRT00033659 (CAS 1401731-54-1) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 1401731-54-1 |
|---|---|
| Molecular Formula | C15H14N4O |
| Molecular Weight | 266.30 g/mol |
| SMILES | CC=1C=2C(=NC=C(C2)C3=CC(NC(C)=O)=CC=C3)NN1 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
MRT00033659 is an effective broad-spectrum kinase inhibitor of CK1 (IC50=0.9 uM for CK1delta) and CHK1 (IC50=0.23 uM). MRT00033659 is a pyrazolo-pyridine analogue. It also induces p53 pathway activation and E2F-1 destabilization.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Solubility data for each compound is provided on the TargetMol product page and DataSheet, listed as maximum solubility in DMSO and/or aqueous media (mg/mL and mM). For compounds not yet characterized, prepare a test dissolution at the intended stock concentration and visually confirm clarity before use. When preparing aqueous working solutions, always dilute from a DMSO stock and monitor for precipitation at your final assay concentration.
After the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
