| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human MS4A14 was used as the immunogen for the MS4A14 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
MS4A14 Antibody / Membrane spanning 4 domains subfamily A member 14 is a anti-MS4A14 Rabbit antibody Recombinant Rabbit Monoclonal clone 29M80 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human.
Key elements and design rationale
- Target: MS4A14
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 29M80, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB
Biological background
Although the specific role of MS4A14 remains under investigation, proteins in the MS4A family are often involved in immune cell activation, receptor signaling, and calcium flux regulation. Several MS4A proteins, including MS4A1 (CD20), have well characterized roles in immune function and are targeted in therapeutic antibody development. MS4A14 antibody helps extend this research to uncover potential similarities in structure and function within the family.
MS4A14 expression has been observed in various tissues, with elevated levels reported in certain cancers. Gene expression analyses suggest MS4A14 may contribute to tumor biology, making MS4A14 antibody useful for cancer biomarker discovery and validation. In addition, large scale genomic studies have linked MS4A family members to neurological conditions, including Alzheimer disease, highlighting potential roles in neural signaling and degeneration.
MS4A14 antibody is commonly used in western blotting, immunohistochemistry, and flow cytometry. These applications reveal protein abundance, cellular localization, and surface expression patterns. Such approaches aid in clarifying whether MS4A14 functions in immune regulation, neurological processes, or oncogenic pathways.
By providing reagents such as MS4A14 antibody,
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
