MS934

SKU:BHB20443515
Overview
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MS934 (CAS 2756323-15-4) is a mapk pathway inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity MAPK Pathway Inhibitor
CAS No. 2756323-15-4
Molecular Weight 1104.11 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T79143-5MG 5 mg
T79143-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg, 50 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T79143
Activity
  • MAPK Pathway Inhibitor
Cas No. 2756323-15-4
Molecular Weight 1104.11
Product Type
  • Small Molecule Inhibitor
Signaling Pathway MAPK
Target MEK

Compound Overview

MS934 (CAS 2756323-15-4) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 2756323-15-4
Molecular Formula C52H69F3IN7O6S
Molecular Weight 1104.11 g/mol
Form Solid
Shipping Room Temperature (RT)

Biological Activity

MS934, a novel VHL-recruiting MEK 1/2 degrader, exhibits potent anti-proliferative effects on HT-29 cell growth, achieving a GI50 of 0.023 uM. It holds potential for researching various human cancers including melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, primary brain tumors, and hepatocellular carcinoma (1).

Target(s): MEK

Signaling pathway(s): MAPK

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does prolonged sonication affect the compound structure?

It is recommended to sonicate at a lower frequency

How to set the concentration of stock solution?

The concentration of stock solution should be lower than the solubility provided on the official website. Within this range, the concentration of stock solution should be set based on that of working solution. For cell experiments, it is recommended to set the stock solution concentration at least 1000 times higher than that of working solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today