| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-icosenoic acid |
| Cas No. | |
| Form | Off-White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in 2 mg/ml of methanol, DMSO (25 mg/ml; heat briefly in boiling water bath) or in dilute base (5 mg/ml; 50 mM NaOH) |
| Source | Synthetic |
| Storage |
Myriocin, also known as ISP-1, is a potent inhibitor of serine palmitoyltransferase, the enzyme responsible for the first step in sphingolipid biosynthesis. In neuroscience, Myriocin is used to study the impact of sphingolipid metabolism on neuronal survival, inflammation, and synaptic function. Its immunosuppressive properties and ability to modulate lipid signaling pathways make it relevant in models of neuroinflammation and neurodegeneration.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label wherepossible)
Risk Phrases:
R22- Harmful if swallowed
Hazard Phrases:
H301
Precautionary Phrases:
P301 + P310
Myriocin (ISP-1) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-233)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Miyake Y., Kozutsumi Y., Nakamura S., Fujita T. and Kawasaki T. (1995) Biochem Piophys Res Commun. 211(2): 396-403.
