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Compound Overview
N-5-Carboxypentyl-1-deoxynojirimycin (CAS 79206-51-2) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 79206-51-2 |
|---|---|
| Molecular Formula | C12H23NO6 |
| Molecular Weight | 277.32 g/mol |
| SMILES | OC(CH)1(CH)(O)(CH)(O)(CH)(O)CN1CCCCCC(O)=O |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
1-Deoxynojirimycin, a potent glucose analog, inhibits alpha-glucosidase I and II effectively. Its derivative, N-5-Carboxypentyl-1-deoxynojirimycin, serves as a ligand for glucosidase I and II purification, utilizing carboxypentyl groups for affinity chromatography resin linkage. Furthermore, N-5-Carboxypentyl-1-deoxynojirimycin demonstrates comparable or superior inhibition of glucosidase compared to 1-deoxynojirimycin, with inhibition constants (Ki) of 0.45 uM and 2.1 uM, respectively, for pig liver glucosidase I.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Solid-form products can be stored at -20°C for more than 3 years. Stock solutions are typically stored at -80°C and can be stored for more than 1 year. It is recommended to aliquot the product to avoid repeated freeze-thaw cycles. For short-term storage, samples can be kept at 4°C for more than one week.
For normal mice, the concentration of DMSO should be kept below 10%. For nude mice, transgenic mice, or mice with weak tolerance, the concentration of DMSO should be kept below 2%. For inhibitors being used for the first time, it is recommended to perform a solvent-negative control experiment to confirm that the solvent has no nonspecific effects on the animals.
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