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Compound Overview
N6F11 (CAS 851398-76-0) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 851398-76-0 |
|---|---|
| Molecular Formula | C13H8Cl2N2OS |
| Molecular Weight | 311.19 g/mol |
| SMILES | ClCC1=NC2=C(SC(=C2)C2=CC=C(Cl)C=C2)C(=O)N1 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
N6F11 is a novel, selective and potent inducer of iron death with anticancer and antitumour activity that promotes GPX4 degradation by binding to TRIM25 in cancer cells.N6F11 can be used to study pancreatic cancer.
Target(s): GPX
Signaling pathway(s): oxidation-reduction
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.
mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.
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