Product Overview
Research Use OnlyThe NF-E2 DNA binding protein is composed of two subunits, p45 and MafK, and it regulates expression of globin genes in developing erythroid cells through interaction with Maf recognition elements (MAREs). A family of NF-E2-related proteins, which are collectively known as the cap ‘n’ collar (CNC) family and include NFE2L1 (also designated TCF11), Nrf2 and Nrf3, are bZIP transcription factors that heterodimerize with Maf proteins to bind MARE sequences. The Nrf proteins also bind the antioxidant response element (ARE) and are implicated in the regulation of detoxification enzymes and the oxida
Validated Applications
| Western Blot (WB) | 1:1000 |
|---|
Key Specifications
| Host Species | Mouse |
|---|---|
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Molecular Weight | Predicted band size:67KDa Observed band size:72KDa |
| Catalog No. | MB0168 |
| UniProt | Q14494 |
| Alternative Names | NFE2L1HBZ17; NFE2L1; TCF11; TCF-11; Transcription factor HBZ17; Transcription factor LCR-F1; Transcription factor 11; Locus control region-factor 1; NF-E2-related factor 1; NFE2-related factor 1; Nuclear factor erythroid 2-related factor 1 |
Immunogen / Antigen
Recombinant full length Human NFE2L1.
Reactivity Notes
This antibody detects endogenous levels of NFE2L1 and does not cross-react with related proteins
Storage & Handling
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Safety
For Research Use Only (RUO). Not intended for diagnostic, therapeutic, or veterinary use. Handle according to standard laboratory biosafety guidelines. Avoid skin and eye contact. Dispose of waste in accordance with local regulations.
This antibody has been validated for: Western Blot. For each application, follow the recommended dilutions on the product datasheet and optimize empirically for your sample type.
WB: 1:1000
This antibody has been confirmed reactive against: Human. Cross-reactivity with other species may occur due to sequence homology but is not guaranteed without independent validation.
Recombinant full length Human NFE2L1.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Avoid repeated freeze-thaw cycles. Centrifuge vials briefly before opening. Dilute immediately before use.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
