| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Nikkomycin Z from Streptomyces tendae |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Nikkomycin Z (CAS 59456-70-1) is a research-grade small molecule supplied by TargetMol.
Alternative names: Nikkomycin Z from Streptomyces tendae
Physical Properties
| CAS Number | 59456-70-1 |
|---|---|
| Molecular Formula | C20H25N5O10 |
| Molecular Weight | 495.44 g/mol |
| SMILES | O(CH)1(CH)(O(C)((CH)(NC((CH)((CH)((CH)(O)C2=CC=C(O)C=N2)C)N)=O)C(O)=O)… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects, acarids and yeasts.
Target(s): Others, Antibiotic, Antifungal
Signaling pathway(s): Microbiology/Virology, Others
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
When solubility is listed as < 1 mg/mL, the compound dissolves to less than 1 mg per milliliter in water at 25 °C, pH 7.4. Such compounds require an organic co-solvent such as DMSO to prepare a concentrated stock, which is then diluted into aqueous assay buffer. For cell-based assays, keep the final DMSO concentration below 0.1% (v/v) to avoid solvent-induced cytotoxicity.
It is not recommended to store DMSO stock solutions at room temperature. Once the stock solution is prepared, aliquot into single-use volumes and store at −20 °C (or −80 °C for sensitive compounds). Room-temperature storage accelerates chemical degradation and moisture uptake. When ready to use, thaw an aliquot at room temperature, use immediately, and avoid repeated freeze-thaw cycles.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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