NpFR1

SKU:BHB11900023
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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NpFR1 is a research-grade small-molecule probe for Reversible fluorescence intensity-based redox sensor for Cancer and Oxidative Stress studies. Supplied as a red solid (MW 431.45) soluble in DMSO; store at -20°C. For research use only.
Molecular Formula C23H21N5O4
Application Notes Reversible fluorescence intensity-based redox sensor
Options selector
Catalog no. Size
SIH-181-1MG 1 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: Blue Ice or 4ºC.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-181
Activity
  • Redox Probe
Form Red Solid
Molecular Weight 431.45
Product Type
  • Biochemicals
  • Small Molecules
Shipping Blue Ice or 4ºC
SMILES C1(N(C(C2=CC5=C(C3=CC=CC1=C23)N(C4=NC(NC(C4=N5)=O)=O)CCC)=O)CCCC)=O
Solubility Soluble in DMSO
Source Synthetic
Storage -20ºC

NpFR1 (Napthalimide-Flavin Redox Sensor 1) is a highly sensitive fluorescent probe that exhibits a dramatic increase in fluorescence upon oxidation. Its reversible redox behavior allows for dynamic monitoring of oxidative stress in live cells. In neuroscience, NpFR1 is particularly useful for detecting redox fluctuations in neuronal environments, aiding in the study of neurodegenerative conditions such as ALS and Parkinson’s disease. Its high signal-to-noise ratio and responsiveness to mild oxidants make it ideal for tracking oxidative damage in neural tissues.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

NpFR1 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-181)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Yeow J., Kaur A.K., Anscomb M.D., and New E.J. (2014) Chem. Commun. 50: 8181-8184.

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