| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | NU7026 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
NU 7026 (CAS 154447-35-5) is a research-grade small molecule supplied by TargetMol.
Alternative names: NU7026
Physical Properties
| CAS Number | 154447-35-5 |
|---|---|
| Molecular Formula | C17H15NO3 |
| Molecular Weight | 281.31 g/mol |
| SMILES | O=C1C=2C(=C3C(=CC2)C=CC=C3)OC(=C1)N4CCOCC4 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 uM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibition against both ATM and ATR.
Target(s): Apoptosis, ATM/ATR, PI3K, DNA-PK
Signaling pathway(s): DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling, Apoptosis
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Sonication time depends on compound solubility and concentration. In most cases, 1–3 minutes of intermittent bath sonication is sufficient to dissolve small molecule compounds in DMSO. For poorly soluble compounds, warming the solvent to 37–50 °C combined with brief vortexing between sonication pulses can improve dissolution. If the compound remains undissolved, prepare a more dilute stock solution.
There are various standards for defining the purity, and we do not have fixed purity standard. The purity of most products are above 98% and can be used for control experiments, including cell experiments, animal experiments, general laboratory experiments, and high-throughput screening. Our product purity also meets the industrial standard.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
