Oditrasertib

SKU:BHB20436982
Overview
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Oditrasertib (CAS 2252271-93-3) is a kinase inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Kinase Inhibitor
CAS No. 2252271-93-3
Molecular Weight 295.28 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T69726-1MG 1 mg
T69726-1MLX10MM 1 mL x 10 mM (in DMSO)
T69726-5MG 5 mg
T69726-10MG 10 mg
T69726-25MG 25 mg
T69726-50MG 50 mg
T69726-100MG 100 mg
T69726-500MG 500 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mg, 1 mL x 10 mM (in DMSO), 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T69726
Activity
  • Kinase Inhibitor
Alternative Names DNL-788
Cas No. 2252271-93-3
Molecular Weight 295.28
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Apoptosis///NF-kappab
SMILES NCC1=CN=CC2=C1OCCN(C(=O)C(C)(C)C(F)F)C2
Target RIP kinase

Compound Overview

Oditrasertib (CAS 2252271-93-3) is a research-grade small molecule supplied by TargetMol.

Alternative names: DNL-788

Physical Properties

CAS Number 2252271-93-3
Molecular Formula C14H15F2N3O2
Molecular Weight 295.28 g/mol
SMILES NCC1=CN=CC2=C1OCCN(C(=O)C(C)(C)C(F)F)C2
Form Solid
Shipping Room Temperature (RT)

Biological Activity

Oditrasertib (DNL-788) is a potent RIPKl inhibitor with an IC50 value of less than 100 nM.Oditrasertib can be used for the study of immune and neurological disorders such as multiple sclerosis and Alzheimer's disease.

Target(s): RIP kinase

Signaling pathway(s): Apoptosis, NF-kappab

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Can high-temperature sterilization be used for inhibitors?

Most small molecule inhibitors are not compatible with autoclaving (121 °C), which can cause thermal decomposition or loss of biological activity. For sterile cell-based experiments, filter-sterilize working solutions through a 0.2 µm membrane after dilution into aqueous buffer. Verify thermal stability in the DataSheet before applying any heat treatment.

How do you ensure the quality and purity of compounds?

The structure of compounds is confirmed through HNMR and purity is verified through HPLC or LCMS, with most compounds having a purity of over 98%. Each batch comes with a Certificate of Analysis (COA), and testing reports are also displayed on our official website.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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