Oridonin

Oridonin is a covalent inhibitor of the NLRP3 inflammasome with potent anti-inflammatory properties. It has demonstrated efficacy in reducing vascular inflammation and modulating PI3K/AKT signaling. In neurodegenerative disease research, Oridonin is being explored for its ability to suppress neuroinflammation, inhibit aberrant signaling pathways, and induce apoptosis in pathological cell populations.

Classification: Warning. Hazard Statements: H351. Precautionary Statements: P203, P280, P318, P405, and P501

Oridonin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-624)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).