Osu03012

SKU:BHB20414511
Overview
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Osu03012 (CAS 742112-33-0) is a small molecule inhibitor supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Small Molecule Inhibitor
CAS No. 742112-33-0
Molecular Weight 460.45 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T2466-2MG 2 mg
T2466-5MG 5 mg
T2466-1MLX10MM 1 mL x 10 mM (in DMSO)
T2466-10MG 10 mg
T2466-25MG 25 mg
T2466-50MG 50 mg
T2466-100MG 100 mg
T2466-200MG 200 mg
T2466-500MG 500 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 2 mg, 5 mg, 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T2466
Activity
  • Small Molecule Inhibitor
Alternative Names Osu 03012
Cas No. 742112-33-0
Molecular Weight 460.45
Product Type
  • Small Molecule Inhibitor
Signaling Pathway PI3K/Akt/mTOR signaling
SMILES C(F)(F)(F)C=1C=C(N(N1)C2=CC=C(NC(CN)=O)C=C2)C3=CC=4C(C=C3)=C5C(=CC4)C=CC=C5
Target PDK

Compound Overview

Osu03012 (CAS 742112-33-0) is a research-grade small molecule supplied by TargetMol.

Alternative names: Osu 03012

Physical Properties

CAS Number 742112-33-0
Molecular Formula C26H19F3N4O
Molecular Weight 460.45 g/mol
SMILES C(F)(F)(F)C=1C=C(N(N1)C2=CC=C(NC(CN)=O)C=C2)C3=CC=4C(C=C3)=C5C(=CC4)C=…
Form Solid
Shipping Room Temperature (RT)

Biological Activity

Osu03012 (AR-12) is an orally bioavailable, small-molecule, celecoxib-derived inhibitor of phosphoinositide-dependent kinase-1 (PDK1) with potential antineoplastic activity.

Target(s): PDK

Signaling pathway(s): PI3K/Akt/mTOR signaling

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Does the product need to be protected from light?

Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.

Why can't I see anything in the vial when I receive small-sized products?

Due to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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