PF-CBP1

SKU:BHB20428052
Overview
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PF-CBP1 (CAS 1962928-21-7) is a epigenetic modulator supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Epigenetic Modulator
CAS No. 1962928-21-7
Molecular Weight 488.62 g/mol
Form Solid
Shipping Room Temperature
Options selector
Catalog no. Size
T3973-1MLX10MM 1 mL x 10 mM (in DMSO)
T3973-10MG 10 mg
T3973-25MG 25 mg
T3973-50MG 50 mg
T3973-100MG 100 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 mL x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No T3973
Activity
  • Epigenetic Modulator
Cas No. 1962928-21-7
Molecular Weight 488.62
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Chromatin/Epigenetic
SMILES C(CN1CCOCC1)N2C=3C(N=C2CCC4=CC=C(OCCC)C=C4)=CC(=CC3)C=5C(C)=NOC5C
Target Epigenetic Reader Domain

Compound Overview

PF-CBP1 (CAS 1962928-21-7) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 1962928-21-7
Molecular Formula C29H36N4O3
Molecular Weight 488.62 g/mol
SMILES C(CN1CCOCC1)N2C=3C(N=C2CCC4=CC=C(OCCC)C=C4)=CC(=CC3)C=5C(C)=NOC5C
Form Solid
Shipping Room Temperature (RT)

Biological Activity

PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).

Target(s): Epigenetic Reader Domain

Signaling pathway(s): Chromatin/Epigenetic

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

What equipment should be used for ultrasound?

Use a bath-type ultrasonic cleaner rather than a high-intensity ultrasonic disruptor. Bath sonicators provide gentle, uniform agitation appropriate for dissolving solid compounds without generating cavitation damage or excessive heat. Ensure the solvent tube is fully submerged and use short sonication pulses of 5–10 seconds.

What is the solubility of the product?

Solubility data for each compound is provided on the TargetMol product page and DataSheet, listed as maximum solubility in DMSO and/or aqueous media (mg/mL and mM). For compounds not yet characterized, prepare a test dissolution at the intended stock concentration and visually confirm clarity before use. When preparing aqueous working solutions, always dilute from a DMSO stock and monitor for precipitation at your final assay concentration.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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