| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Product Type | |
| Signaling Pathway | |
| Target |
Compound Overview
PITCOIN4 is a research-grade small molecule supplied by TargetMol.
Physical Properties
| Form | Solid |
|---|---|
| Shipping | Room Temperature (RT) |
Biological Activity
PITCOIN4 is a Class II Alpha PI3K-C2alpha inhibitor with high selectivity, demonstrating nanomolar inhibition of PI3K-C2alpha and exhibiting over 100-fold selectivity against a broad kinase panel (1).
Target(s): PI3K
Signaling pathway(s): PI3K/Akt/mTOR signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Try the following steps: (1) warm the DMSO solvent to 37–50 °C before adding the compound; (2) vortex vigorously for 30 seconds then bath-sonicate for 1–2 minutes; (3) if still undissolved, prepare a more dilute stock. Note that maximum solubility values are reference conditions — actual solubility can vary with temperature, solvent lot, and compound batch. Contact BioHippo support if dissolution problems persist.
Stock concentration (mM) = [mass (mg) × 1000] / [MW (g/mol) × volume (mL)]. Example: to prepare 10 mM stock from 5 mg of a 500 g/mol compound: volume = (5 × 1000) / (500 × 10) = 1 mL DMSO. For working solutions, dilute the DMSO stock into assay buffer: C₁V₁ = C₂V₂. For a 1 µM working solution from a 10 mM stock in a 1 mL assay volume, add 0.1 µL of stock (or pre-dilute to an intermediate concentration first).
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
