| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Pyrvinium embonate |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Pyrvinium pamoate (CAS 3546-41-6) is a research-grade small molecule supplied by TargetMol.
Alternative names: Pyrvinium embonate
Physical Properties
| CAS Number | 3546-41-6 |
|---|---|
| Molecular Formula | C26H28N3 . 1/2 C23H14O6 |
| Molecular Weight | 575.70 g/mol |
| SMILES | CN(C)c1ccc2(n+)(C)c(C=Cc3cc(C)n(c3C)-c3ccccc3)ccc2c1.CN(C)c1ccc2(n+)(C… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug due to its inhibition of Wnt/beta-catenin pathway in some types of cancer.
Target(s): Wnt/beta-catenin
Signaling pathway(s): Stem Cells, Cytoskeletal Signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Most small molecule inhibitors are not compatible with autoclaving (121 °C), which can cause thermal decomposition or loss of biological activity. For sterile cell-based experiments, filter-sterilize working solutions through a 0.2 µm membrane after dilution into aqueous buffer. Verify thermal stability in the DataSheet before applying any heat treatment.
After the stock solution is prepared, it is typically stored at -80°C and can be kept for over 1 year. It is recommended to aliquot to avoid repeated freeze-thaw cycles. For frequent use, it can be stored at 4°C for over a week.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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