| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Troponin T, fast skeletal muscle, TnTf, Beta-TnTF, Fast skeletal muscle troponin T (fTnT). |
| Expression System | |
| Form | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | |
| Product Type | |
| Purity | |
| Solubility | It is recommended to reconstitute the lyophilized TNNT3 in buffer containing 0.01M HCl, pH 2.0 not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Source | Escherichia Coli. |
| Species | |
| Storage | |
| Target |
Recombinant human Fast Skeletal Troponin T is supplied as a recombinant protein for in vitro research use.
Background
Troponin T3 Fast Skeletal Type (TNNT3) is a pivotal protein in the regulation of muscle contraction, specifically in fast-twitch skeletal muscles. The TNNT3 human recombinant, a product of cutting-edge biotechnology, offers a powerful tool to delve into the intricate molecular characteristics and multifaceted roles of this essential protein. This research aims to shed light on the molecular intricacies of TNNT3 and explore its significance beyond muscle contraction. At its core, TNNT3 plays a central role in the troponin complex, which orchestrates muscle contraction by modulating the interaction between actin and myosin filaments. This molecular complex regulates muscle contraction in response to calcium ions (Ca²⁺), a fundamental process underpinning skeletal muscle function. TNNT3, as a specific isoform of troponin T, contributes to the fine-tuning of muscle contractility. The importance of TNNT3 extends beyond its role in muscle physiology. It is primarily expressed in fast-twitch skeletal muscles responsible for rapid, forceful movements, such as sprinting and jumping. Consequently, TNNT3 is critical for the precise control of fast muscle contractions, ensuring optimal performance during activities requiring speed and power. Furthermore, TNNT3 has gained recognition for its potential relevance in various neuromuscular disorders. Mutations in the TNNT3 gene have been associated with congenital myopathies, highlighting its clinical significance. Investigating the structural and functional properties of TNNT3 can provide valuable insights into the molecular basis of these disorders and potentially pave the way for therapeutic interventions. The TNNT3 human recombinant serves as a gateway to comprehending the intricacies of this protein's molecular functions and its potential applications beyond muscle contraction. Researchers can leverage this recombinant protein to unravel TNNT3's structural properties, interactions with other muscle proteins, and its implications in neuromuscular diseases. This research endeavor aims to offer a comprehensive analysis of the TNNT3 human recombinant, emphasizing its molecular characteristics, functional roles in muscle contraction, and its relevance in the context of neuromuscular disorders. By exploring the multifaceted nature of TNNT3, we aspire to contribute to a deeper understanding of muscle biology and the potential development of novel therapeutic strategies.
Product format
Provided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.
What is the purity of Recombinant human Fast Skeletal Troponin T (Human)?
What buffer / formulation is this protein supplied in?
How should Recombinant human Fast Skeletal Troponin T (Human) be stored?
What expression system was used to produce this protein?
Is this protein approved for clinical or in vitro diagnostic use?
Can I request a custom size, tag variant, or formulation?
Can’t Find What You’re Looking For? We can help you source the best match or customize a recombinant protein solution for your study. Options may include species (human/mouse/rat), protein region/domain (full-length vs fragment), tag or label (His/GST/FLAG/biotin/fluorescent), expression system (E. coli/HEK293/insect), purity grade, formulation (buffer, carrier-free, glycerol-free), activity/functional validation (binding or enzymatic assays), endotoxin level (low-endotoxin for cell-based work), mutants/variants (point mutations, isoforms), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
