| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Transducin Beta Chain 3, G Protein, Beta-3 Subunit, GTP-Binding Regulatory Protein Beta-3 Chain, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3, Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-3, Hypertension Associated Protein, Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 3, GNB3. |
| Concentration | |
| Expression System | |
| Form | Sterile Filtered clear solution. |
| Formulation | |
| Product Type | |
| Protein Length | |
| Protein Size | |
| Purity | |
| Source | Escherichia Coli. |
| Species | |
| Storage | |
| Target |
Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3 is supplied as a recombinant protein for in vitro research use.
Background
GNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition, this polymorphism is also linked with the occurrence of the splice variant GNB3-s, which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3, however they have not been fully described. Among the diseases associated with GNB3 are syncope, and aortic coarctation.
Product format
Provided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.
What is the purity of Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3 (Human)?
What buffer / formulation is this protein supplied in?
How should Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3 (Human) be stored?
What expression system was used to produce this protein?
Is this protein approved for clinical or in vitro diagnostic use?
Can I request a custom size, tag variant, or formulation?
Can’t Find What You’re Looking For? We can help you source the best match or customize a recombinant protein solution for your study. Options may include species (human/mouse/rat), protein region/domain (full-length vs fragment), tag or label (His/GST/FLAG/biotin/fluorescent), expression system (E. coli/HEK293/insect), purity grade, formulation (buffer, carrier-free, glycerol-free), activity/functional validation (binding or enzymatic assays), endotoxin level (low-endotoxin for cell-based work), mutants/variants (point mutations, isoforms), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
