| Field | Specification |
|---|---|
| Mfr No | |
| Cellular Localization | |
| Expression System | |
| Form | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | |
| Product Type | |
| Protein Length | |
| Protein Size | |
| Purity | |
| Solubility | It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. |
| Source | Escherichia Coli. |
| Species | |
| Storage | |
| Target |
Recombinant Human Uncoupling protein 3 is supplied as a recombinant protein for in vitro research use.
Background
Uncoupling protein 3 (UCP3) is a mitochondrial protein which takes part in energy metabolism and thermoregulation. UCP3 Function Proton Uncoupling - UCP3 helps dissipate the proton gradient across the inner mitochondrial membrane. This uncoupling leads to the production of heat instead of ATP, a necessary process for thermogenesis. Energy Regulation - UCP3 takes part in the regulation of energy expenditure and can influence metabolic efficiency. UCP3 Location UCP3 is predominantly expressed in skeletal muscle and brown adipose tissue, where its activity is critical for energy metabolism. UCP3 Role in Metabolism according to some studies, UCP3 may improve insulin sensitivity and help manage body weight. In addition, UCP3 participates in the metabolism of fatty acids and may help reduce the accumulation of reactive oxygen species (ROS) by decreasing oxidative stress. UCP3 Regulation UCP3 expression can raise in response to physical activity, emphasising its role in adapting to varius energy demands during exercise. Changes in UCP3 levels have been associated with diabetes, obesity and other metabolic disorders. Clinical Relevance UCP3 is being investigated as a potential target for obesity and metabolic disease treatments because of its role in energy balance UCP3 is a central player in energy metabolism and thermogenesis, with implications for metabolic health and the body's response to exercise and diet.
Product format
Provided as a recombinant protein suitable for in vitro workflows such as binding studies, screening, and assay development. Refer to the specifications table for expression format and molecular properties.
What is the purity of Recombinant Human Uncoupling protein 3 (Human)?
What buffer / formulation is this protein supplied in?
How should Recombinant Human Uncoupling protein 3 (Human) be stored?
What expression system was used to produce this protein?
Is this protein approved for clinical or in vitro diagnostic use?
Can I request a custom size, tag variant, or formulation?
Can’t Find What You’re Looking For? We can help you source the best match or customize a recombinant protein solution for your study. Options may include species (human/mouse/rat), protein region/domain (full-length vs fragment), tag or label (His/GST/FLAG/biotin/fluorescent), expression system (E. coli/HEK293/insect), purity grade, formulation (buffer, carrier-free, glycerol-free), activity/functional validation (binding or enzymatic assays), endotoxin level (low-endotoxin for cell-based work), mutants/variants (point mutations, isoforms), and bulk or custom packaging. Click Talk to a Scientist to submit a request form, email us at support@biohippo.com, or explore our Research Services for additional support. Our team will be in contact with you shortly.
