| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for the recombinant TAG-72 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target |
Overview
Recombinant TAG-72 Antibody is an antibody targeting TAG-72. Host: Mouse. Monoclonal. Clone: rTAG72/9132. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: TAG-72.
- Immunogen: A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for the recombinant….
- Species reactivity: Human.
- Localization: Cytoplasm, Cell Surface.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.