| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | CAD-1883 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Rimtuzalcap (CAS 2167246-24-2) is a research-grade small molecule supplied by TargetMol.
Alternative names: CAD-1883
Physical Properties
| CAS Number | 2167246-24-2 |
|---|---|
| Molecular Formula | C18H24F2N6O |
| Molecular Weight | 378.42 g/mol |
| SMILES | N(C=1N=C(N=C(C1)N2CCOCC2)N3N=C(C)C=C3)C4CCC(F)(F)CC4 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Rimtuzalcap (CAD-1883) (CAD-1883), a pioneering selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels), is employed in the study of movement disorders such as spinocerebellar ataxia (SCA) and essential tremor (ET).
Target(s): Potassium Channel
Signaling pathway(s): Membrane transporter/Ion channel
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.
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