| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | KRAS G12D IN 18 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
RMC-9805 (CAS 2922732-54-3) is a research-grade small molecule supplied by TargetMol.
Alternative names: KRAS G12D IN 18
Physical Properties
| CAS Number | 2922732-54-3 |
|---|---|
| Molecular Formula | C63H88F3N11O7 |
| Molecular Weight | 1168.44 g/mol |
| SMILES | C(C(F)(F)F)N1C(=C2C=3C1=CC=C(C3)N4C(C)(C(CH)(NC((CH)(N5C(C)6(CC5)CN(C(… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Yes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.
Stock concentration (mM) = [mass (mg) × 1000] / [MW (g/mol) × volume (mL)]. Example: to prepare 10 mM stock from 5 mg of a 500 g/mol compound: volume = (5 × 1000) / (500 × 10) = 1 mL DMSO. For working solutions, dilute the DMSO stock into assay buffer: C₁V₁ = C₂V₂. For a 1 µM working solution from a 10 mM stock in a 1 mL assay volume, add 0.1 µL of stock (or pre-dilute to an intermediate concentration first).
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
