| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | SB415286 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
SB 415286 (CAS 264218-23-7) is a research-grade small molecule supplied by TargetMol.
Alternative names: SB415286
Physical Properties
| CAS Number | 264218-23-7 |
|---|---|
| Molecular Formula | C16H10ClN3O5 |
| Molecular Weight | 359.72 g/mol |
| SMILES | N(C1=C(C(=O)NC1=O)C2=C(N(=O)=O)C=CC=C2)C3=CC(Cl)=C(O)C=C3 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
SB 415286 is a potent GSK3alpha inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3beta.
Target(s): Apoptosis, GSK-3
Signaling pathway(s): Stem Cells, Apoptosis, PI3K/Akt/mTOR signaling
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.
If you are using DMSO for preparation,sterilization is not recommended, as DMSO itself possesses strong sterilizing properties. The prepared solution is sterile. For further assurance, it can be left overnight at 4°C. The safest method is to filter through a specialized organic filter membrane. If water is used for preparation,sterilization can be achieved by filtering through a 0.22 μm filter membrane.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
