| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | SC514 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
SC-514 (CAS 354812-17-2) is a research-grade small molecule supplied by TargetMol.
Alternative names: SC514
Physical Properties
| CAS Number | 354812-17-2 |
|---|---|
| Molecular Formula | C9H8N2OS2 |
| Molecular Weight | 224.30 g/mol |
| SMILES | C(N)(=O)C=1SC(=CC1N)C=2C=CSC2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 uM), obstructs NF-kappaB-dependent gene expression.
Target(s): p38 MAPK, Serine Protease, Aurora Kinase, CDK, IkappaB/IKK
Signaling pathway(s): Proteases/Proteasome, Chromatin/Epigenetic, Cell Cycle/Checkpoint, NF-kappab, MAPK
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.
For currently available products, batch-specific purity data (HPLC chromatogram, NMR spectrum, and Certificate of Analysis) is accessible via the DataSheet link on the product page. For future or custom synthesis products, purity determination is conducted upon availability and published on the product page. Contact BioHippo for batch-specific CoA requests or custom synthesis enquiries.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
