| Field | Specification |
|---|---|
| Activity | |
| Alternative Names | MBX-8025 lysine dihydrate |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
Seladelpar Lysine dihydrate (CAS 928821-40-3) is a research-grade small molecule supplied by TargetMol.
Alternative names: MBX-8025 lysine dihydrate
Physical Properties
| CAS Number | 928821-40-3 |
|---|---|
| Molecular Formula | C27H41F3N2O9S |
| Molecular Weight | 626.68 g/mol |
| SMILES | NCCCC(CH)(N)C(O)=O.OC(COC1=C(C=C(C=C1)SC(CH)(OCC)COC2=CC=C(C=C2)C(F)(F… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Seladelpar lysine, a selective PPAR-delta agonist, is used for the therapy of Homozygous Familial Hypercholesterolemia (HoFH).
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Most small molecule inhibitors are not compatible with autoclaving (121 °C), which can cause thermal decomposition or loss of biological activity. For sterile cell-based experiments, filter-sterilize working solutions through a 0.2 µm membrane after dilution into aqueous buffer. Verify thermal stability in the DataSheet before applying any heat treatment.
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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